Brief Introduction To 8-hydroxyquinoline Copper

Update:05-11-2019
Summary:

  Description of copper 8-hydroxyquinoline: widely used […]

  Description of copper 8-hydroxyquinoline: widely used in the determination and separation of metals.

  8-hydroxyquinoline copper trait: It is a white or light yellow crystal or a crystalline powder. Do not dissolve in water and ether, soluble in ethanol, acetone, chloroform, benzene or dilute acid, can sublimate. Less corrosive.

  8-hydroxyquinoline copper biological application:

  (1) It is a partial inhibitor of ribonuclease and is added to an organic extraction buffer containing phenol to prevent oxidation of phenol to phenyl hydrazine, and the concentration is usually 0.1% (1 g/L). The addition of 8-hydroxyquinoline copper makes the phenol: chloroform bright yellow, which helps to distinguish the organic phase and the aqueous phase when the nuclei acid is separated and purified. After binding to VDR, the 8-hydroxyquinoline copper changed from bright yellow to dark green. If the extracted organic phenol is yellow, all of the VDRs have been removed.

  (2) Widely used in the determination and separation of metals. Can be combined with Cu+2, Mg+2, Ca+2, Sr+2, Ba+2, Zn+2, Cd+2, Al+3, Ga+3, In+3, Yt+3, La+3, Various metal ions such as Pb+2, Cr+3, Mn+2, Fe+3, Co+2, Ni+2, and Pd+2 are complex.

  Storage conditions: sealed and stored in a cool and dry place;

  Acute toxicity: toxic, the half-lethal dose of mice in the abdominal cavity is 48mg/kg.

  Note: 8-hydroxyquinoline copper is toxic, so be careful when using it.